Polynucleotides in Belfast: Why Skin Regeneration Is Replacing Filler

Advanced Plinest treatments at Laser & Skin Belfast

In aesthetic medicine, the focus is shifting. Rather than adding volume or changing facial shape, more people are asking for treatments that repair, strengthen, and improve skin quality.

This is why polynucleotides have become one of the most in-demand treatments in advanced aesthetics — particularly for delicate areas like the under-eyes, face, neck, and hands.

At Laser & Skin Belfast, we use Plinest polynucleotides, a clinically established regenerative injectable designed to improve skin health at a cellular level.

What are polynucleotides?

Polynucleotides are purified DNA fragments that work by supporting the skin’s natural repair mechanisms.

When injected into the skin, they help to:

• Stimulate fibroblast activity (cells responsible for collagen and elastin)

• Improve skin elasticity and hydration

• Strengthen thin or fragile skin

• Support tissue repair and regeneration

• Reduce inflammation and oxidative stress

Rather than filling or lifting, polynucleotides improve the quality and function of the skin itself.

Why polynucleotides are replacing filler for many people

Traditional dermal fillers are designed to add volume or structure. While they still have a place, they are not always suitable — especially in areas where the skin is thin or where overfilling can look unnatural.

Polynucleotides are increasingly chosen because they:

• Do not add volume

• Do not change facial shape

• Do not create heaviness or puffiness

• Improve skin quality gradually and naturally

  
  

This makes them particularly popular for:

• Under-eye concerns

• Early signs of ageing

• Crepey or fragile skin

• Clients who want subtle, natural improvement

  
  

What is Plinest?

Plinest is a medical-grade polynucleotide formulation widely used in regenerative and aesthetic medicine.

It is valued for its ability to:

• Improve skin density and resilience

• Support collagen and elastin production

• Improve hydration and elasticity

• Strengthen compromised or ageing skin

Plinest is often used where filler is inappropriate or where the goal is skin repair rather than volume.

How Plinest polynucleotides work in the skin

Once injected, Plinest polynucleotides act as biostimulators within the dermis.

They:

1. Activate fibroblasts

2. Improve cellular repair and turnover

3. Enhance hydration at a dermal level

4. Strengthen the skin matrix over time

Results are progressive, developing over several weeks as the skin responds biologically to the treatment.

What areas can be treated with polynucleotides?

Plinest polynucleotides are commonly used for:

• Under-eye area (dark circles, crepey texture, thin skin)

• Face (overall skin quality and early ageing)

• Neck

• Décolletage

• Hands

• Areas of sun damage or fragile skin

They are especially effective in areas where the skin has lost strength rather than volume.

What results can you expect?

Polynucleotides do not create instant transformation. Instead, clients typically notice:

• Improved skin texture

• Better hydration and elasticity

• Reduced crepiness

• Healthier, more resilient-looking skin

• Subtle softening of fine lines

Results continue to improve over time, making this a long-term skin investment rather than a quick fix.

How many treatments are needed?

Polynucleotides work best as a course of treatments.

Typically:

• An initial course is recommended

• Sessions are spaced several weeks apart

• Maintenance treatments may be advised depending on skin condition and goals

Your treatment plan is tailored during consultation based on your skin, concerns, and expectations.

What does treatment and recovery involve?

Treatment involves small injections using fine needles or a cannula, depending on the area.

You may experience:

• Mild stinging during treatment

• Temporary redness or swelling

• Small injection bumps that settle within hours to days

• Occasional bruising

Downtime is usually minimal, but treatment should be planned around important events.

Who are polynucleotides best suited for?

Plinest polynucleotides are ideal if you:

• Want to improve skin quality, not add volume

• Have thin, crepey, or ageing skin

• Are concerned about the under-eye area

• Prefer natural, regenerative treatments

• Want long-term improvement rather than instant change

They are often combined with laser or skin-based treatments as part of a wider skin plan.

The Laser & Skin Belfast approach

At Laser & Skin Belfast, polynucleotides are used strategically, not as a trend treatment.

This means:

• Full consultation and skin assessment

• Honest advice on suitability

• Clear explanation of realistic outcomes

• Tailored treatment planning

• Focus on long-term skin health

If polynucleotides are not the right option for your skin, you will be advised accordingly.

Book a polynucleotide consultation in Belfast

If you’re looking to improve skin quality, resilience, and regeneration — particularly in delicate areas — Plinest polynucleotides may be an excellent option.

A consultation at Laser & Skin Belfast will assess:

• Suitability for treatment

• Areas to be treated

• Number of sessions recommended

• How polynucleotides fit into your overall skin plan

Modern aesthetics is about repairing skin, not masking problems.

Book A Consultation